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Is rifampin a strong antibiotic? Rifampin is in a class of medications called antimycobacterials. It works by killing the bacteria that cause infection. Antibiotics such as rifampin will not work for colds, flu, or other viral infections. Why should rifampin rifadin be taken on an empty stomach? You should take rifampicin 'on an empty stomach '. This means that you should take your doses about an hour before a meal, or wait until two hours afterwards. This is because your body absorbs less rifampicin if taken at the same time as food, which means it is less effective.
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