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How much amoxicillin can I take at once? You can take amoxicillin with or without food. A common dose of amoxicillin for an adult with a mild to moderate ear, nose, or throat infection is 500 mg every 12 hours or 250 mg every 8 hours until the prescription is finished. What happens if you don't take all your antibiotics? But this advice is not only wrong, it could actually be harmful. The idea that you have to take all the antibiotics you 're prescribed is based on the assumption that all the bacteria causing the infection have to be killed, so the surviving minority don't become resistant. How long do side effects last after taking amoxicillin? In mild cases, diarrhea may last up to 14 days after you stop taking the antibiotic. In more severe cases, the symptoms may not go away until several weeks after you start treatment. The symptoms may also come back after treatment.
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