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How does Epogen work in the body? Erythropoietin is a protein that normally is made in the body by the kidney. It causes the bone marrow to produce oxygen-carrying red blood cells. Epogen and Procrit are both epoetin alfa, but they are marketed by two different pharmaceutical companies. How long does it take for an injection of Epogen take to work? It takes time for your body to make new red blood cells and raise your hemoglobin (Hb) level. With EPOGEN treatment, Hb levels usually increase in 2 to 6 weeks. Your doctor will test your blood regularly—at least weekly at the beginning of your treatment—to make sure EPOGEN is working.
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