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How does ropinirole work in the body? Ropinirole is also used to treat restless legs syndrome (RLS). It may improve your sleep by decreasing the urge to move your legs and decreasing uncomfortable/unpleasant feelings in the legs. This medication works by helping to restore the balance of a certain natural substance (dopamine) in the brain.
Is Requip addictive? Research published in 2010 found that reducing the dosage of dopamine-agonist drugs such as Ropinirole can cause acute withdrawal symptoms that are similar to those experienced by some people who are addicted to cocaine. Researchers have called these symptoms dopamine agonist withdrawal syndrome, or DAWS.
How do dopamine agonists work in Parkinson disease? In effect, the brain is tricked into thinking it is receiving the dopamine it needs. In general, dopamine agonist are not as potent as carbidopa/levodopa and may be less likely to cause dyskinesias. The two most commonly prescribed oral pill agonists in the U.S. are pramipexole (Mirapex) and ropinirole (Requip).
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